BDBM50081537 CHEMBL3422092

SMILES [H][C@]12CC[C@@]([H])(CC(O)C1)N2c1ccc(cc1)-c1n[nH]c2ccc(cc12)C(=O)N[C@H](C1CC1)c1ccccn1

InChI Key

Data  1 KI  15 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081537   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081537(CHEMBL3422092)
Affinity DataIC50:  250nMAssay Description:Inhibition of human Ret V804L mutant by millipore radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081537(CHEMBL3422092)
Affinity DataIC50:  280nMAssay Description:Inhibition of human Ret V804M mutant by millipore radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081537(CHEMBL3422092)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human Ret by millipore radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed